The U.S. Highway 281 and Loop 1604 interchange will be closed this weekend, according to the Texas Department of Transportation. Read More

North Expansion Project work continues, and closures on Highway 281 are planned for this weekend, according to the Texas Department of Transportation. Read More

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From 9 p.m. on Friday until 5 a.m. on Monday, the interchange of U.S. 281 at Loop 1604 will be mostly or partly closed as construction crews work to install steel beams as part of the Loop 1604 North ... Read More

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THE WICHITA COUNTY CEMETERY CURRENTLY LOOKS LIKE AN OPEN FIELD OFF OF HIGHWAY 281. IN TIME, A NEW ENTRANCE WILL BE ON THE WAY. Read More

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A devastating three-vehicle accident on US Highway 281 in Blanco resulted in three fatalities and left several others critically injured on Wedn ... Read More

One child and two adults were killed in a multi-vehicle crash on U.S. Highway 281 in Blanco County on Wednesday. Read More

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Planned road construction in northwest Kansas will create a 75-mile detour. Starting Monday, March 17, the Kansas Department of Transportation will close just a 3.5-mile stretch of U.S. Highway 281 ... Read More

According to Fire Chief Patrick J. Thomas social media reports, firefighters from Alice and Ben Bolt were working on a wildfire on Highway 281 and Farm-to-Market Road 1554 this afternoon. Motorists ... Read More

EDGELEY, N.D. (KFGO) - A 38-year-old Jamestown man was seriously injured in a crash on U.S. Highway 281 Friday in Lamoure County. The crash happened shortly before 6 p.m. at the intersection of County ... Read More

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Icy conditions are impacting a major San Antonio highwaya Saturday morning as cold rain continues to fall across the city, according to TxDOT. Read More

Read full article: How Texas' drought conditions are impacting ... parked on the shoulder of the southbound lanes of I-37, near U.S. Highway 281, when he was struck by another driver, police ... Read More

San Antonio highways are no strangers to tragic incidents, with the most recent one taking the life of a 52-year-old man. A vehicle reportedly struck and killed a man on Highway 281 Friday night, ... Read More

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Nearby, a crash has blocked off two lanes at U.S. 281 N ... A crash near downtown San Antonio Friday night impacted traffic, forcing drivers off the highway. Read More

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Highway 281 in San Antonio is experiencing delays in San Antonio as new fiber cables are being installed across the highway. Read More

The Texas Department of Transportation is reporting construction work will cause them to shut down parts of Highway 281 near Evens Road and Encino Rio. '?Closure will be on US 281 between Encino ... Read More

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A Spokane man was killed early Saturday morning after his speeding 2020 Tesla went off Highway 281 in George and landed in a tow yard next to the highway. Read More

The completion of U.S. Highway 281 on the North Side was a primary factor in that decrease. U.S. Highway 281 was once the most congested corridor in San Antonio and among the top 15 across the state. Read More

The St. Paul Police Department was called to a single-vehicle rollover crash near Highway 281 and Adams Street on Saturday at 1:20 a.m. Read More

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(KSAT) SAN ANTONIO - Several lanes that were closed after a rollover on southbound Highway 281 near The Quarry reopened on Tuesday morning, according to Transguide cameras in the area. Read More

A man has gone viral on Reddit for protesting near U.S. Highway 281 in San Antonio holding a large anti-Nazi sign that depicts billionaire Elon Musk giving his now-infamous post-inauguration salute. Read More